1039 lines
30 KiB
JSON
1039 lines
30 KiB
JSON
{
|
|
"B_specific_contamination": {
|
|
"B_specific_E_depression_sum_with_exact_replay": 12.473553121089935,
|
|
"B_specific_unique_edges": 13,
|
|
"B_specific_unique_source_KC": 11,
|
|
"B_specific_update_rows": 2654,
|
|
"causal_route_fractions": {
|
|
"MBON_DAN_feedback": null,
|
|
"direct_A_driven": null,
|
|
"olfactory_feedback": null,
|
|
"recurrent_KC": null,
|
|
"unresolved": 1.0
|
|
},
|
|
"endogenous_DAN_as_gate_fraction_in_frozen_model": 0.0,
|
|
"event_coincidence_1ms_included_B_update_fraction": 0.0,
|
|
"excluded_nonmatching_B_rows": 10,
|
|
"excluded_nonmatching_trace_rows": 160,
|
|
"external_matched_US_gate_fraction": 1.0,
|
|
"first_B_specific_update_pairing_by_seed": {
|
|
"51201": 1,
|
|
"51202": 1,
|
|
"51203": 1,
|
|
"51204": 1,
|
|
"51205": 1
|
|
},
|
|
"first_activation_only_included_B_update_fraction": 1.0,
|
|
"reason": "Whole-brain source spike timing plus a positive anatomical edge is not proof of membrane-spike causation. Frozen Phase 4M history has no causal predecessor trace. Do not assign invented path percentages.",
|
|
"shadow_short_tau_20ms_excluded_B_update_fraction": 0.0,
|
|
"shadow_short_tau_20ms_weighted_eligibility_ratio_to_frozen": 0.07983898740818457,
|
|
"temporal_credit_event_counts": {
|
|
"long_trace_>20ms": 2654
|
|
},
|
|
"temporal_credit_weighted_fraction": {
|
|
"long_trace_>20ms": 1.0
|
|
},
|
|
"unmatched_runtime_rows": 0
|
|
},
|
|
"B_specific_timed_input_candidates": {
|
|
"APL_graded_inhibition_in_source_decomposition": false,
|
|
"audited_B_specific_KC": 59,
|
|
"causal_predecessor_unambiguously_identified": false,
|
|
"exact_frozen_edge_and_delay_used": true,
|
|
"five_synaptic_tau_lookback_ms": 25.0,
|
|
"linked_B_specific_plastic_update_rows": 183,
|
|
"linked_updates_with_timed_input": 183,
|
|
"not_interpretable_as_causal_source_percentages": true,
|
|
"rows": 415,
|
|
"source_class_of_strongest_timing_compatible_positive_input": {
|
|
"PN/olfactory": 415
|
|
}
|
|
},
|
|
"CSI_curve": [
|
|
{
|
|
"CSI": 0.0,
|
|
"pairings": 0
|
|
},
|
|
{
|
|
"CSI": -7.67733409282963e-05,
|
|
"pairings": 1
|
|
},
|
|
{
|
|
"CSI": -0.00015606915457683327,
|
|
"pairings": 2
|
|
},
|
|
{
|
|
"CSI": 0.000519788155009709,
|
|
"pairings": 5
|
|
},
|
|
{
|
|
"CSI": 0.001679602436035227,
|
|
"pairings": 10
|
|
},
|
|
{
|
|
"CSI": 0.004251456216824177,
|
|
"pairings": 20
|
|
},
|
|
{
|
|
"CSI": 0.008161064054743355,
|
|
"pairings": 30
|
|
},
|
|
{
|
|
"CSI": 0.011437046811776486,
|
|
"pairings": 40
|
|
},
|
|
{
|
|
"CSI": 0.015089317490016971,
|
|
"pairings": 50
|
|
},
|
|
{
|
|
"CSI": 0.022815420445899143,
|
|
"pairings": 60
|
|
},
|
|
{
|
|
"CSI": 0.037048033185904924,
|
|
"pairings": 75
|
|
},
|
|
{
|
|
"CSI": 0.052433504136864685,
|
|
"pairings": 100
|
|
}
|
|
],
|
|
"DAN": {
|
|
"additional_all_DAN_shadow_E_depression_sum_mean_100": 6.7690910339355455,
|
|
"all_DAN_shadow_E_depression_sum_mean_100": 34.740484619140624,
|
|
"all_DAN_shadow_interpretation": "counterfactual open-loop teaching-gate interpretation; not frozen model and not measured dopamine concentration",
|
|
"confirmed_type_counts": {
|
|
"PAM11": 480,
|
|
"PAM15": 396,
|
|
"PPL103": 28364
|
|
},
|
|
"endogenous_spike_cluster_counts": {
|
|
"PAM": 876,
|
|
"PPL1": 28364
|
|
},
|
|
"external_only_E_depression_sum_mean_100": 27.971393585205078,
|
|
"frozen_Phase4M_endogenous_DAN_teaching_gate_count": 0,
|
|
"matched_compartment_spikes": 396,
|
|
"matched_endogenous_DAN_spikes_total": 396,
|
|
"source_breakdown": [
|
|
{
|
|
"E_depression_sum": 90.11731344461441,
|
|
"gates": 396,
|
|
"source": "endogenous-feedback-associated"
|
|
},
|
|
{
|
|
"E_depression_sum": 83.58510708808899,
|
|
"gates": 500,
|
|
"source": "external-US-associated"
|
|
}
|
|
],
|
|
"trial_count": 500
|
|
},
|
|
"candidate_gate": {
|
|
"causal_B_contamination_route_identified": false,
|
|
"external_vs_endogenous_distinguished": true,
|
|
"isolated_and_wholebrain_majority_improvement_demonstrated": false
|
|
},
|
|
"candidate_generated": false,
|
|
"control_wholebrain": {
|
|
"A_D0_and_frozen_E1_effect_are_exactly_zero_by_E_identity": true,
|
|
"conditions": [
|
|
{
|
|
"A_minus_B_mean": -4.2,
|
|
"A_specific_seeds": 0,
|
|
"condition": "A+random-US-timing",
|
|
"pairings": 50
|
|
},
|
|
{
|
|
"A_minus_B_mean": -0.8,
|
|
"A_specific_seeds": 1,
|
|
"condition": "A+random-US-timing",
|
|
"pairings": 100
|
|
},
|
|
{
|
|
"A_minus_B_mean": -3.2,
|
|
"A_specific_seeds": 0,
|
|
"condition": "A+unrelated-compartment-US",
|
|
"pairings": 50
|
|
},
|
|
{
|
|
"A_minus_B_mean": -1.8,
|
|
"A_specific_seeds": 1,
|
|
"condition": "A+unrelated-compartment-US",
|
|
"pairings": 100
|
|
},
|
|
{
|
|
"A_minus_B_mean": -3.4,
|
|
"A_specific_seeds": 0,
|
|
"condition": "B+matched-US",
|
|
"pairings": 50
|
|
},
|
|
{
|
|
"A_minus_B_mean": -5.0,
|
|
"A_specific_seeds": 1,
|
|
"condition": "B+matched-US",
|
|
"pairings": 100
|
|
}
|
|
],
|
|
"frozen_E1_reference_reused_per_evaluation_seed": true,
|
|
"rows": 60,
|
|
"total_brain_wall_seconds": 73.81998237699372
|
|
},
|
|
"controls": {
|
|
"A_D0": "ANALYTIC-EXACT-IDENTITY",
|
|
"A_matched_US": "RUN-PHASE4M-TRAJECTORY-RECONSTRUCTED",
|
|
"B_matched_US": "RUN-INDEPENDENT-100-PAIRING-TRAJECTORY",
|
|
"all_DAN_closed_loop": false,
|
|
"all_DAN_gate": "RUN-OPEN-LOOP-SHADOW-100-PAIRING-TRAJECTORY",
|
|
"external_US_only": "RUN-IDENTICAL-TO-PHASE4M",
|
|
"frozen_E1": "ANALYTIC-EXACT-IDENTITY",
|
|
"full_control_matrix_pass": false,
|
|
"independent_results": "controls/independent-summary.json",
|
|
"independent_wholebrain": "controls/wholebrain-summary.json",
|
|
"random_US_timing": "RUN-INDEPENDENT-100-PAIRING-TRAJECTORY",
|
|
"unrelated_compartment_US": "RUN-INDEPENDENT-100-PAIRING-TRAJECTORY"
|
|
},
|
|
"edge_groups": {
|
|
"A-specific": 105,
|
|
"B-specific": 221,
|
|
"inactive": 13537,
|
|
"shared": 369
|
|
},
|
|
"event_trace_reproduction": {
|
|
"all_passed": false,
|
|
"audited_trial_count": 500,
|
|
"mismatched_count": 2,
|
|
"mismatched_trials": [
|
|
{
|
|
"max_abs_eligibility_error": 0.12266039848327637,
|
|
"pairing": 40,
|
|
"seed": 51202
|
|
},
|
|
{
|
|
"max_abs_eligibility_error": 0.12266039848327637,
|
|
"pairing": 39,
|
|
"seed": 51203
|
|
}
|
|
],
|
|
"next_trial_overlay_restored_from_sealed_Phase4M_history": true
|
|
},
|
|
"frozen_integrity": {
|
|
"all_passed": false,
|
|
"dynamic_regression_all_passed": false,
|
|
"phase4c_reference_replay_first": {
|
|
"all_passed": false,
|
|
"auditory-100hz": {
|
|
"max_abs_g_error": 0.00048828125,
|
|
"max_abs_voltage_error": 6.103515625e-05,
|
|
"per_neuron_counts_exact": true,
|
|
"spike_events_exact": true
|
|
},
|
|
"auditory-10hz": {
|
|
"max_abs_g_error": 0.00048828125,
|
|
"max_abs_voltage_error": 3.0517578125e-05,
|
|
"per_neuron_counts_exact": true,
|
|
"spike_events_exact": true
|
|
},
|
|
"gustatory-50hz": {
|
|
"max_abs_g_error": 0.00390625,
|
|
"max_abs_voltage_error": 6.103515625e-05,
|
|
"per_neuron_counts_exact": true,
|
|
"spike_events_exact": true
|
|
},
|
|
"mechanosensory-50hz": {
|
|
"max_abs_g_error": 444.85986328125,
|
|
"max_abs_voltage_error": 314.9923400878906,
|
|
"per_neuron_counts_exact": false,
|
|
"spike_events_exact": false
|
|
},
|
|
"olfactory-50hz": {
|
|
"max_abs_g_error": 0.001953125,
|
|
"max_abs_voltage_error": 6.103515625e-05,
|
|
"per_neuron_counts_exact": true,
|
|
"spike_events_exact": true
|
|
}
|
|
},
|
|
"phase4c_reference_replay_second": {
|
|
"all_passed": false,
|
|
"auditory-100hz": {
|
|
"max_abs_g_error": 0.0009765625,
|
|
"max_abs_voltage_error": 6.103515625e-05,
|
|
"per_neuron_counts_exact": true,
|
|
"spike_events_exact": true
|
|
},
|
|
"auditory-10hz": {
|
|
"max_abs_g_error": 0.000244140625,
|
|
"max_abs_voltage_error": 3.0517578125e-05,
|
|
"per_neuron_counts_exact": true,
|
|
"spike_events_exact": true
|
|
},
|
|
"gustatory-50hz": {
|
|
"max_abs_g_error": 0.001953125,
|
|
"max_abs_voltage_error": 6.103515625e-05,
|
|
"per_neuron_counts_exact": true,
|
|
"spike_events_exact": true
|
|
},
|
|
"mechanosensory-50hz": {
|
|
"max_abs_g_error": 444.85986328125,
|
|
"max_abs_voltage_error": 314.9923400878906,
|
|
"per_neuron_counts_exact": false,
|
|
"spike_events_exact": false
|
|
},
|
|
"olfactory-50hz": {
|
|
"max_abs_g_error": 0.00048828125,
|
|
"max_abs_voltage_error": 6.103515625e-05,
|
|
"per_neuron_counts_exact": true,
|
|
"spike_events_exact": true
|
|
}
|
|
},
|
|
"static": {
|
|
"frozen_hashes_unchanged": true,
|
|
"phase1_to_3b": true,
|
|
"phase4m": true,
|
|
"previous_phases": true
|
|
},
|
|
"static_checksums_all_passed": true
|
|
},
|
|
"functional_collapse_first_checkpoint": 100,
|
|
"gate_specificity": {
|
|
"all_DAN_branch_status": "counterfactual open-loop shadow gate, not frozen Phase 4M dynamics or physiological dopamine",
|
|
"external_US_only_is_frozen_Phase4M_rule": true,
|
|
"isolated": [
|
|
{
|
|
"A_specific_seeds": 4,
|
|
"A_spike_L1": 0.4,
|
|
"B_spike_L1": 0.2,
|
|
"mechanism": "all-confirmed-DAN-shadow",
|
|
"pairings": 20
|
|
},
|
|
{
|
|
"A_specific_seeds": 2,
|
|
"A_spike_L1": 0.8,
|
|
"B_spike_L1": 1.2,
|
|
"mechanism": "all-confirmed-DAN-shadow",
|
|
"pairings": 50
|
|
},
|
|
{
|
|
"A_specific_seeds": 1,
|
|
"A_spike_L1": 0.8,
|
|
"B_spike_L1": 1.4,
|
|
"mechanism": "all-confirmed-DAN-shadow",
|
|
"pairings": 60
|
|
},
|
|
{
|
|
"A_specific_seeds": 1,
|
|
"A_spike_L1": 0.8,
|
|
"B_spike_L1": 1.4,
|
|
"mechanism": "all-confirmed-DAN-shadow",
|
|
"pairings": 75
|
|
},
|
|
{
|
|
"A_specific_seeds": 1,
|
|
"A_spike_L1": 0.8,
|
|
"B_spike_L1": 1.4,
|
|
"mechanism": "all-confirmed-DAN-shadow",
|
|
"pairings": 100
|
|
},
|
|
{
|
|
"A_specific_seeds": 3,
|
|
"A_spike_L1": 0.0,
|
|
"B_spike_L1": 0.0,
|
|
"mechanism": "external-only",
|
|
"pairings": 20
|
|
},
|
|
{
|
|
"A_specific_seeds": 4,
|
|
"A_spike_L1": 0.8,
|
|
"B_spike_L1": 0.4,
|
|
"mechanism": "external-only",
|
|
"pairings": 50
|
|
},
|
|
{
|
|
"A_specific_seeds": 4,
|
|
"A_spike_L1": 0.8,
|
|
"B_spike_L1": 0.4,
|
|
"mechanism": "external-only",
|
|
"pairings": 60
|
|
},
|
|
{
|
|
"A_specific_seeds": 3,
|
|
"A_spike_L1": 0.8,
|
|
"B_spike_L1": 0.8,
|
|
"mechanism": "external-only",
|
|
"pairings": 75
|
|
},
|
|
{
|
|
"A_specific_seeds": 1,
|
|
"A_spike_L1": 0.8,
|
|
"B_spike_L1": 1.4,
|
|
"mechanism": "external-only",
|
|
"pairings": 100
|
|
}
|
|
],
|
|
"isolated_exact_prefix_only": [
|
|
{
|
|
"A_specific_seeds": 4,
|
|
"A_spike_L1": 0.4,
|
|
"B_spike_L1": 0.2,
|
|
"clean_seed_count": 5,
|
|
"mechanism": "all-confirmed-DAN-shadow",
|
|
"pairings": 20
|
|
},
|
|
{
|
|
"A_specific_seeds": 1,
|
|
"A_spike_L1": 0.6666666666666666,
|
|
"B_spike_L1": 1.3333333333333333,
|
|
"clean_seed_count": 3,
|
|
"mechanism": "all-confirmed-DAN-shadow",
|
|
"pairings": 50
|
|
},
|
|
{
|
|
"A_specific_seeds": 0,
|
|
"A_spike_L1": 0.6666666666666666,
|
|
"B_spike_L1": 1.6666666666666667,
|
|
"clean_seed_count": 3,
|
|
"mechanism": "all-confirmed-DAN-shadow",
|
|
"pairings": 60
|
|
},
|
|
{
|
|
"A_specific_seeds": 0,
|
|
"A_spike_L1": 0.6666666666666666,
|
|
"B_spike_L1": 1.6666666666666667,
|
|
"clean_seed_count": 3,
|
|
"mechanism": "all-confirmed-DAN-shadow",
|
|
"pairings": 75
|
|
},
|
|
{
|
|
"A_specific_seeds": 0,
|
|
"A_spike_L1": 0.6666666666666666,
|
|
"B_spike_L1": 1.6666666666666667,
|
|
"clean_seed_count": 3,
|
|
"mechanism": "all-confirmed-DAN-shadow",
|
|
"pairings": 100
|
|
},
|
|
{
|
|
"A_specific_seeds": 3,
|
|
"A_spike_L1": 0.0,
|
|
"B_spike_L1": 0.0,
|
|
"clean_seed_count": 5,
|
|
"mechanism": "external-only",
|
|
"pairings": 20
|
|
},
|
|
{
|
|
"A_specific_seeds": 2,
|
|
"A_spike_L1": 0.6666666666666666,
|
|
"B_spike_L1": 0.6666666666666666,
|
|
"clean_seed_count": 3,
|
|
"mechanism": "external-only",
|
|
"pairings": 50
|
|
},
|
|
{
|
|
"A_specific_seeds": 2,
|
|
"A_spike_L1": 0.6666666666666666,
|
|
"B_spike_L1": 0.6666666666666666,
|
|
"clean_seed_count": 3,
|
|
"mechanism": "external-only",
|
|
"pairings": 60
|
|
},
|
|
{
|
|
"A_specific_seeds": 1,
|
|
"A_spike_L1": 0.6666666666666666,
|
|
"B_spike_L1": 1.3333333333333333,
|
|
"clean_seed_count": 3,
|
|
"mechanism": "external-only",
|
|
"pairings": 75
|
|
},
|
|
{
|
|
"A_specific_seeds": 0,
|
|
"A_spike_L1": 0.6666666666666666,
|
|
"B_spike_L1": 1.6666666666666667,
|
|
"clean_seed_count": 3,
|
|
"mechanism": "external-only",
|
|
"pairings": 100
|
|
}
|
|
],
|
|
"isolated_replay_wall_seconds": 3.6956715250089474,
|
|
"nonexact_trials": [
|
|
{
|
|
"max_abs_eligibility_error": 0.12266039848327637,
|
|
"pairing": 40,
|
|
"seed": 51202
|
|
},
|
|
{
|
|
"max_abs_eligibility_error": 0.12266039848327637,
|
|
"pairing": 39,
|
|
"seed": 51203
|
|
}
|
|
],
|
|
"wholebrain": [
|
|
{
|
|
"A_minus_B_mean": -1.2,
|
|
"A_specific_seeds": 1,
|
|
"mechanism": "all-confirmed-DAN-shadow",
|
|
"pairings": 60
|
|
},
|
|
{
|
|
"A_minus_B_mean": -2.0,
|
|
"A_specific_seeds": 1,
|
|
"mechanism": "all-confirmed-DAN-shadow",
|
|
"pairings": 100
|
|
},
|
|
{
|
|
"A_minus_B_mean": -5.2,
|
|
"A_specific_seeds": 0,
|
|
"mechanism": "external-only",
|
|
"pairings": 60
|
|
},
|
|
{
|
|
"A_minus_B_mean": -1.6,
|
|
"A_specific_seeds": 1,
|
|
"mechanism": "external-only",
|
|
"pairings": 100
|
|
}
|
|
],
|
|
"wholebrain_wall_seconds": 49.23106441800701
|
|
},
|
|
"generalization_onset_pairings_by_predeclared_CSI_rule": null,
|
|
"group_curves": [
|
|
{
|
|
"group": "A-specific",
|
|
"mean_delta_E": 0.0,
|
|
"pairings": 0,
|
|
"weighted_transmission_reduction": 0.0
|
|
},
|
|
{
|
|
"group": "B-specific",
|
|
"mean_delta_E": 0.0,
|
|
"pairings": 0,
|
|
"weighted_transmission_reduction": 0.0
|
|
},
|
|
{
|
|
"group": "inactive",
|
|
"mean_delta_E": 0.0,
|
|
"pairings": 0,
|
|
"weighted_transmission_reduction": 0.0
|
|
},
|
|
{
|
|
"group": "shared",
|
|
"mean_delta_E": 0.0,
|
|
"pairings": 0,
|
|
"weighted_transmission_reduction": 0.0
|
|
},
|
|
{
|
|
"group": "A-specific",
|
|
"mean_delta_E": -0.0008114139083772898,
|
|
"pairings": 1,
|
|
"weighted_transmission_reduction": 0.0017858551407354962
|
|
},
|
|
{
|
|
"group": "B-specific",
|
|
"mean_delta_E": -0.00019647066328616348,
|
|
"pairings": 1,
|
|
"weighted_transmission_reduction": 0.0005355863915934305
|
|
},
|
|
{
|
|
"group": "inactive",
|
|
"mean_delta_E": -5.529318195840461e-06,
|
|
"pairings": 1,
|
|
"weighted_transmission_reduction": 1.7181444391994978e-05
|
|
},
|
|
{
|
|
"group": "shared",
|
|
"mean_delta_E": -0.0006014676415361464,
|
|
"pairings": 1,
|
|
"weighted_transmission_reduction": 0.0018626284816637925
|
|
},
|
|
{
|
|
"group": "A-specific",
|
|
"mean_delta_E": -0.0016024403739720583,
|
|
"pairings": 2,
|
|
"weighted_transmission_reduction": 0.0035361883106772483
|
|
},
|
|
{
|
|
"group": "B-specific",
|
|
"mean_delta_E": -0.00038913575699552896,
|
|
"pairings": 2,
|
|
"weighted_transmission_reduction": 0.0010609966055603365
|
|
},
|
|
{
|
|
"group": "inactive",
|
|
"mean_delta_E": -1.0694539560063276e-05,
|
|
"pairings": 2,
|
|
"weighted_transmission_reduction": 3.316572139365e-05
|
|
},
|
|
{
|
|
"group": "shared",
|
|
"mean_delta_E": -0.001192851411178708,
|
|
"pairings": 2,
|
|
"weighted_transmission_reduction": 0.0036922574652540814
|
|
},
|
|
{
|
|
"group": "A-specific",
|
|
"mean_delta_E": -0.004320898558944464,
|
|
"pairings": 5,
|
|
"weighted_transmission_reduction": 0.009681106707497906
|
|
},
|
|
{
|
|
"group": "B-specific",
|
|
"mean_delta_E": -0.0008547037374228239,
|
|
"pairings": 5,
|
|
"weighted_transmission_reduction": 0.0023563029464888454
|
|
},
|
|
{
|
|
"group": "inactive",
|
|
"mean_delta_E": -2.1412889327621088e-05,
|
|
"pairings": 5,
|
|
"weighted_transmission_reduction": 6.647132940873607e-05
|
|
},
|
|
{
|
|
"group": "shared",
|
|
"mean_delta_E": -0.0029612309765070675,
|
|
"pairings": 5,
|
|
"weighted_transmission_reduction": 0.009161318552488197
|
|
},
|
|
{
|
|
"group": "A-specific",
|
|
"mean_delta_E": -0.008691489696502686,
|
|
"pairings": 10,
|
|
"weighted_transmission_reduction": 0.01952891932999961
|
|
},
|
|
{
|
|
"group": "B-specific",
|
|
"mean_delta_E": -0.0016575920162722468,
|
|
"pairings": 10,
|
|
"weighted_transmission_reduction": 0.004574777274475872
|
|
},
|
|
{
|
|
"group": "inactive",
|
|
"mean_delta_E": -4.9367423343937844e-05,
|
|
"pairings": 10,
|
|
"weighted_transmission_reduction": 0.00015127899845878822
|
|
},
|
|
{
|
|
"group": "shared",
|
|
"mean_delta_E": -0.0057692606002092365,
|
|
"pairings": 10,
|
|
"weighted_transmission_reduction": 0.017849316893964386
|
|
},
|
|
{
|
|
"group": "A-specific",
|
|
"mean_delta_E": -0.01747841536998749,
|
|
"pairings": 20,
|
|
"weighted_transmission_reduction": 0.03916034447357663
|
|
},
|
|
{
|
|
"group": "B-specific",
|
|
"mean_delta_E": -0.0029337296262383463,
|
|
"pairings": 20,
|
|
"weighted_transmission_reduction": 0.007979305372225545
|
|
},
|
|
{
|
|
"group": "inactive",
|
|
"mean_delta_E": -0.00010018079628935084,
|
|
"pairings": 20,
|
|
"weighted_transmission_reduction": 0.00030486579677189025
|
|
},
|
|
{
|
|
"group": "shared",
|
|
"mean_delta_E": -0.011246236599981784,
|
|
"pairings": 20,
|
|
"weighted_transmission_reduction": 0.03490888825675245
|
|
},
|
|
{
|
|
"group": "A-specific",
|
|
"mean_delta_E": -0.026202268525958063,
|
|
"pairings": 30,
|
|
"weighted_transmission_reduction": 0.05874096381934639
|
|
},
|
|
{
|
|
"group": "B-specific",
|
|
"mean_delta_E": -0.0038078823126852512,
|
|
"pairings": 30,
|
|
"weighted_transmission_reduction": 0.010389518445722692
|
|
},
|
|
{
|
|
"group": "inactive",
|
|
"mean_delta_E": -0.00016724702436476946,
|
|
"pairings": 30,
|
|
"weighted_transmission_reduction": 0.0005054039617856043
|
|
},
|
|
{
|
|
"group": "shared",
|
|
"mean_delta_E": -0.01626170501112938,
|
|
"pairings": 30,
|
|
"weighted_transmission_reduction": 0.050579899764603045
|
|
},
|
|
{
|
|
"group": "A-specific",
|
|
"mean_delta_E": -0.03453723341226578,
|
|
"pairings": 40,
|
|
"weighted_transmission_reduction": 0.07727652673524374
|
|
},
|
|
{
|
|
"group": "B-specific",
|
|
"mean_delta_E": -0.0049045802094042305,
|
|
"pairings": 40,
|
|
"weighted_transmission_reduction": 0.013522593913205932
|
|
},
|
|
{
|
|
"group": "inactive",
|
|
"mean_delta_E": -0.00022900870826561003,
|
|
"pairings": 40,
|
|
"weighted_transmission_reduction": 0.0006915769181994822
|
|
},
|
|
{
|
|
"group": "shared",
|
|
"mean_delta_E": -0.020971396192908286,
|
|
"pairings": 40,
|
|
"weighted_transmission_reduction": 0.06583947992346725
|
|
},
|
|
{
|
|
"group": "A-specific",
|
|
"mean_delta_E": -0.04255176857113838,
|
|
"pairings": 50,
|
|
"weighted_transmission_reduction": 0.09529328977455938
|
|
},
|
|
{
|
|
"group": "B-specific",
|
|
"mean_delta_E": -0.0059387839399278166,
|
|
"pairings": 50,
|
|
"weighted_transmission_reduction": 0.016224803925704506
|
|
},
|
|
{
|
|
"group": "inactive",
|
|
"mean_delta_E": -0.00028701452538371086,
|
|
"pairings": 50,
|
|
"weighted_transmission_reduction": 0.0008648604837594567
|
|
},
|
|
{
|
|
"group": "shared",
|
|
"mean_delta_E": -0.025389956310391426,
|
|
"pairings": 50,
|
|
"weighted_transmission_reduction": 0.0802039722845424
|
|
},
|
|
{
|
|
"group": "A-specific",
|
|
"mean_delta_E": -0.05015785321593284,
|
|
"pairings": 60,
|
|
"weighted_transmission_reduction": 0.11269886821075499
|
|
},
|
|
{
|
|
"group": "B-specific",
|
|
"mean_delta_E": -0.0070442017167806625,
|
|
"pairings": 60,
|
|
"weighted_transmission_reduction": 0.019187120784497087
|
|
},
|
|
{
|
|
"group": "inactive",
|
|
"mean_delta_E": -0.0003334636858198792,
|
|
"pairings": 60,
|
|
"weighted_transmission_reduction": 0.0010027106231981588
|
|
},
|
|
{
|
|
"group": "shared",
|
|
"mean_delta_E": -0.028344783559441568,
|
|
"pairings": 60,
|
|
"weighted_transmission_reduction": 0.08988344776485584
|
|
},
|
|
{
|
|
"group": "A-specific",
|
|
"mean_delta_E": -0.0569388285279274,
|
|
"pairings": 75,
|
|
"weighted_transmission_reduction": 0.12815889068189898
|
|
},
|
|
{
|
|
"group": "B-specific",
|
|
"mean_delta_E": -0.009091752395033837,
|
|
"pairings": 75,
|
|
"weighted_transmission_reduction": 0.024885157084412877
|
|
},
|
|
{
|
|
"group": "inactive",
|
|
"mean_delta_E": -0.000424810906406492,
|
|
"pairings": 75,
|
|
"weighted_transmission_reduction": 0.0012831709568852754
|
|
},
|
|
{
|
|
"group": "shared",
|
|
"mean_delta_E": -0.028784004971385002,
|
|
"pairings": 75,
|
|
"weighted_transmission_reduction": 0.09111085749599408
|
|
},
|
|
{
|
|
"group": "A-specific",
|
|
"mean_delta_E": -0.06418240517377853,
|
|
"pairings": 100,
|
|
"weighted_transmission_reduction": 0.14455626778338143
|
|
},
|
|
{
|
|
"group": "B-specific",
|
|
"mean_delta_E": -0.01132869701832533,
|
|
"pairings": 100,
|
|
"weighted_transmission_reduction": 0.031099236472050477
|
|
},
|
|
{
|
|
"group": "inactive",
|
|
"mean_delta_E": -0.000590769900009036,
|
|
"pairings": 100,
|
|
"weighted_transmission_reduction": 0.0017815365689329073
|
|
},
|
|
{
|
|
"group": "shared",
|
|
"mean_delta_E": -0.029082241281867028,
|
|
"pairings": 100,
|
|
"weighted_transmission_reduction": 0.09212276364651677
|
|
}
|
|
],
|
|
"isolated_curve": [
|
|
{
|
|
"A_MBON_spike_L1": 0.0,
|
|
"A_specific_functional_seeds": 0,
|
|
"A_transmission_reduction_percent": 0.0,
|
|
"B_MBON_spike_L1": 0.0,
|
|
"B_transmission_reduction_percent": 0.0,
|
|
"mean_latency_separation_ms": 0.0,
|
|
"mean_spike_L1_separation": 0.0,
|
|
"pairings": 0
|
|
},
|
|
{
|
|
"A_MBON_spike_L1": 0.0,
|
|
"A_specific_functional_seeds": 0,
|
|
"A_transmission_reduction_percent": 0.4167495261239985,
|
|
"B_MBON_spike_L1": 0.0,
|
|
"B_transmission_reduction_percent": 0.36525857393991557,
|
|
"mean_latency_separation_ms": 0.0,
|
|
"mean_spike_L1_separation": 0.0,
|
|
"pairings": 1
|
|
},
|
|
{
|
|
"A_MBON_spike_L1": 0.0,
|
|
"A_specific_functional_seeds": 1,
|
|
"A_transmission_reduction_percent": 0.8128261000216683,
|
|
"B_MBON_spike_L1": 0.0,
|
|
"B_transmission_reduction_percent": 0.740926713976528,
|
|
"mean_latency_separation_ms": 0.020000000000000285,
|
|
"mean_spike_L1_separation": 0.0,
|
|
"pairings": 2
|
|
},
|
|
{
|
|
"A_MBON_spike_L1": 0.0,
|
|
"A_specific_functional_seeds": 2,
|
|
"A_transmission_reduction_percent": 2.0261885430339426,
|
|
"B_MBON_spike_L1": 0.0,
|
|
"B_transmission_reduction_percent": 1.8589451211680426,
|
|
"mean_latency_separation_ms": 0.020000000000000285,
|
|
"mean_spike_L1_separation": 0.0,
|
|
"pairings": 5
|
|
},
|
|
{
|
|
"A_MBON_spike_L1": 0.0,
|
|
"A_specific_functional_seeds": 2,
|
|
"A_transmission_reduction_percent": 3.9625080280015994,
|
|
"B_MBON_spike_L1": 0.0,
|
|
"B_transmission_reduction_percent": 3.6876356915570043,
|
|
"mean_latency_separation_ms": -0.019999999999998862,
|
|
"mean_spike_L1_separation": 0.0,
|
|
"pairings": 10
|
|
},
|
|
{
|
|
"A_MBON_spike_L1": 0.0,
|
|
"A_specific_functional_seeds": 3,
|
|
"A_transmission_reduction_percent": 7.626873587488314,
|
|
"B_MBON_spike_L1": 0.0,
|
|
"B_transmission_reduction_percent": 7.17468478430239,
|
|
"mean_latency_separation_ms": 1.4210854715202005e-15,
|
|
"mean_spike_L1_separation": 0.0,
|
|
"pairings": 20
|
|
},
|
|
{
|
|
"A_MBON_spike_L1": 0.0,
|
|
"A_specific_functional_seeds": 1,
|
|
"A_transmission_reduction_percent": 10.980786464716621,
|
|
"B_MBON_spike_L1": 0.2,
|
|
"B_transmission_reduction_percent": 10.566984865214092,
|
|
"mean_latency_separation_ms": 0.020000000000001704,
|
|
"mean_spike_L1_separation": -0.2,
|
|
"pairings": 30
|
|
},
|
|
{
|
|
"A_MBON_spike_L1": 0.4,
|
|
"A_specific_functional_seeds": 4,
|
|
"A_transmission_reduction_percent": 14.294776705137275,
|
|
"B_MBON_spike_L1": 0.2,
|
|
"B_transmission_reduction_percent": 13.770812245114474,
|
|
"mean_latency_separation_ms": -7.105427357601002e-16,
|
|
"mean_spike_L1_separation": 0.2,
|
|
"pairings": 40
|
|
},
|
|
{
|
|
"A_MBON_spike_L1": 0.8,
|
|
"A_specific_functional_seeds": 4,
|
|
"A_transmission_reduction_percent": 17.38208670631182,
|
|
"B_MBON_spike_L1": 0.4,
|
|
"B_transmission_reduction_percent": 16.803203764537976,
|
|
"mean_latency_separation_ms": 0.019999999999999574,
|
|
"mean_spike_L1_separation": 0.4,
|
|
"pairings": 50
|
|
},
|
|
{
|
|
"A_MBON_spike_L1": 0.8,
|
|
"A_specific_functional_seeds": 4,
|
|
"A_transmission_reduction_percent": 19.77299057615935,
|
|
"B_MBON_spike_L1": 0.4,
|
|
"B_transmission_reduction_percent": 19.00896338003621,
|
|
"mean_latency_separation_ms": 0.020000000000000285,
|
|
"mean_spike_L1_separation": 0.4,
|
|
"pairings": 60
|
|
},
|
|
{
|
|
"A_MBON_spike_L1": 0.8,
|
|
"A_specific_functional_seeds": 3,
|
|
"A_transmission_reduction_percent": 21.230637835035555,
|
|
"B_MBON_spike_L1": 0.8,
|
|
"B_transmission_reduction_percent": 20.00365725898498,
|
|
"mean_latency_separation_ms": 0.020000000000000285,
|
|
"mean_spike_L1_separation": 0.0,
|
|
"pairings": 75
|
|
},
|
|
{
|
|
"A_MBON_spike_L1": 0.8,
|
|
"A_specific_functional_seeds": 1,
|
|
"A_transmission_reduction_percent": 22.74714310454706,
|
|
"B_MBON_spike_L1": 1.4,
|
|
"B_transmission_reduction_percent": 21.219731071059478,
|
|
"mean_latency_separation_ms": 0.019999999999999574,
|
|
"mean_spike_L1_separation": -0.6,
|
|
"pairings": 100
|
|
}
|
|
],
|
|
"limitations": [
|
|
"Temporal predecessor class unresolved; no causal path attribution percentage claimed",
|
|
"All-DAN efficacy is an open-loop shadow, not a closed-loop retrained brain",
|
|
"Phase 4C mechanosensory frozen regression showed at least one divergent run; static SHA-256 passes but dynamic integrity cannot be called PASS"
|
|
],
|
|
"mechanism_tags": {
|
|
"ENDOGENOUS-DAN-CREDIT-CONTAMINATION": false,
|
|
"GENERALIZATION-ONSET-IDENTIFIED": false,
|
|
"LONG-TRACE-CREDIT-CONTAMINATION": true,
|
|
"NO-SINGLE-DOMINANT-CONTAMINATION-SOURCE": true,
|
|
"RECURRENT-KC-CREDIT-CONTAMINATION": null,
|
|
"SHARED-EDGE-GENERALIZATION-DOMINANT": true,
|
|
"SPECIFICITY-PEAK-IDENTIFIED": true
|
|
},
|
|
"phase": "4N",
|
|
"shared_edge_isolated": [
|
|
{
|
|
"decomposition": "A+shared",
|
|
"latency_delta": 0.279999999999999,
|
|
"odor": "A",
|
|
"spike_L1": 0.4,
|
|
"transmission_reduction": 15.539164640579813
|
|
},
|
|
{
|
|
"decomposition": "A+shared",
|
|
"latency_delta": 0.2799999999999997,
|
|
"odor": "B",
|
|
"spike_L1": 0.2,
|
|
"transmission_reduction": 15.102735170140116
|
|
},
|
|
{
|
|
"decomposition": "A+shared+B",
|
|
"latency_delta": 0.279999999999999,
|
|
"odor": "A",
|
|
"spike_L1": 0.6,
|
|
"transmission_reduction": 16.28630178480409
|
|
},
|
|
{
|
|
"decomposition": "A+shared+B",
|
|
"latency_delta": 0.2799999999999997,
|
|
"odor": "B",
|
|
"spike_L1": 0.4,
|
|
"transmission_reduction": 16.026499064079367
|
|
},
|
|
{
|
|
"decomposition": "A-only",
|
|
"latency_delta": 0.060000000000000143,
|
|
"odor": "A",
|
|
"spike_L1": 0.0,
|
|
"transmission_reduction": 3.909555222654695
|
|
},
|
|
{
|
|
"decomposition": "A-only",
|
|
"latency_delta": 0.0,
|
|
"odor": "B",
|
|
"spike_L1": 0.0,
|
|
"transmission_reduction": 1.8146664499529426
|
|
},
|
|
{
|
|
"decomposition": "all-updated",
|
|
"latency_delta": 0.31999999999999956,
|
|
"odor": "A",
|
|
"spike_L1": 0.8,
|
|
"transmission_reduction": 17.38208670631182
|
|
},
|
|
{
|
|
"decomposition": "all-updated",
|
|
"latency_delta": 0.3,
|
|
"odor": "B",
|
|
"spike_L1": 0.4,
|
|
"transmission_reduction": 16.803203764537976
|
|
}
|
|
],
|
|
"specificity_peak_pairings": 50,
|
|
"status": "PARTIAL-MECHANISM-AUDIT-NO-CANDIDATE",
|
|
"wholebrain_specificity": {
|
|
"at_peak": {
|
|
"isolated_A_minus_B_spike_L1": 0.4,
|
|
"pairings": 50,
|
|
"wholebrain_A_minus_B_spike_L1": -4.8,
|
|
"wholebrain_A_specific_seeds": 1,
|
|
"wholebrain_specificity_penalty": 5.2
|
|
},
|
|
"trajectory": [
|
|
{
|
|
"isolated_A_minus_B_spike_L1": 0.0,
|
|
"pairings": 10,
|
|
"wholebrain_A_minus_B_spike_L1": -0.8,
|
|
"wholebrain_A_specific_seeds": 2,
|
|
"wholebrain_specificity_penalty": 0.8
|
|
},
|
|
{
|
|
"isolated_A_minus_B_spike_L1": 0.0,
|
|
"pairings": 20,
|
|
"wholebrain_A_minus_B_spike_L1": -3.6,
|
|
"wholebrain_A_specific_seeds": 1,
|
|
"wholebrain_specificity_penalty": 3.6
|
|
},
|
|
{
|
|
"isolated_A_minus_B_spike_L1": 0.4,
|
|
"pairings": 50,
|
|
"wholebrain_A_minus_B_spike_L1": -4.8,
|
|
"wholebrain_A_specific_seeds": 1,
|
|
"wholebrain_specificity_penalty": 5.2
|
|
},
|
|
{
|
|
"isolated_A_minus_B_spike_L1": 0.4,
|
|
"pairings": 60,
|
|
"wholebrain_A_minus_B_spike_L1": -5.2,
|
|
"wholebrain_A_specific_seeds": 0,
|
|
"wholebrain_specificity_penalty": 5.6000000000000005
|
|
},
|
|
{
|
|
"isolated_A_minus_B_spike_L1": 0.0,
|
|
"pairings": 75,
|
|
"wholebrain_A_minus_B_spike_L1": -2.8,
|
|
"wholebrain_A_specific_seeds": 0,
|
|
"wholebrain_specificity_penalty": 2.8
|
|
},
|
|
{
|
|
"isolated_A_minus_B_spike_L1": -0.6,
|
|
"pairings": 100,
|
|
"wholebrain_A_minus_B_spike_L1": -1.6,
|
|
"wholebrain_A_specific_seeds": 1,
|
|
"wholebrain_specificity_penalty": 1.0
|
|
}
|
|
]
|
|
}
|
|
}
|