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digital-drosophila/registry/catalog-20260929/evidence/phase4m-kcmbon-efficacy/audit/final-summary.json
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{
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],
"endpoint_100_majority_pass": {
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"multiplicative": false
},
"functional_transfer_gate_scope": "PASS at one or more predeclared pairing checkpoints, not necessarily retained at 100 pairings",
"mechanism_gates": {
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"first_passing_pairing": null,
"pass": false,
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},
"bounded_multiplicative": {
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},
"multiplicative": {
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}
},
"no_dense_time_by_edge_state": true,
"nonmonotonic_functional_output_despite_monotonic_E_depression": true,
"performance": {
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},
"phase4l_additive_reproduced": true,
"postsynaptic_branch_run": false,
"presynaptic_functional_transfer_pass": true,
"same_KC_spikes_DAN_timing_mask_and_seeds": true,
"status": "PASS-KC-MBON-FUNCTIONAL-TRANSFER-v2"
},
"literature_audit": "literature-audit/phase4m_literature_audit.json",
"performance": {
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"dense_time_by_edge_state": false,
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"overlay_checkpoint_bytes_total": 78700,
"paired_overlay_runtime": {
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"baseline_loop_seconds_mean": 1.2220882470002834,
"baseline_total_call_seconds_mean": 1.2258025214003283,
"biological_duration_ms": 120.0,
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"bounded_E100_total_call_seconds_mean": 1.2242864740001096,
"five_paired_seeds": true,
"loop_overhead_percent_mean": -0.07358484609854424,
"loop_overhead_seconds_mean": -0.0009046418001162238,
"mean_peak_VRAM_bytes": 341479219.2,
"numeric_results_not_reused_for_gates": true,
"total_call_overhead_seconds_mean": -0.0015160474002186674,
"trial": "frozen ODOR_A 120 ms, paired evaluation seed, no dopamine or learning"
},
"peak_RAM_kib": 2870208,
"peak_VRAM_bytes": 341523968,
"whole_brain_mean_post_wall_seconds": 1.2878333504500687
},
"phase": "4M",
"phase4n_started": false,
"postsynaptic": {
"branch_defined": true,
"combined_presynaptic_postsynaptic_run": false,
"global_MBON_threshold_modified": false,
"reason": "postsynaptic nAChR evidence exists in adult Drosophila, but a quantitative rule for exact MaleCNS y5B'2a target and its receptor map is unavailable",
"run": false,
"status": "AUDIT-ONLY-NOT-RUN-COMPARTMENT-SPECIFIC-QUANTITATIVE-RULE-UNKNOWN"
},
"whole_brain": {
"direct_feedback_vs_shared_edge_causal_disambiguation": "NOT-ESTABLISHED; no feedback edge ablation was authorized",
"endpoint_100_E_identity": {
"bounded_multiplicative": {
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"E_reduction_sum_mean": 6.739152526855468,
"changed_edges_mean": 29.0
},
"B-specific": {
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},
"inactive": {
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},
"shared": {
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}
},
"multiplicative": {
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"changed_edges_mean": 29.0
},
"B-specific": {
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},
"inactive": {
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"E_reduction_sum_mean": 8.015281772613525,
"changed_edges_mean": 109.8
},
"shared": {
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"E_reduction_sum_mean": 16.92964973449707,
"changed_edges_mean": 43.0
}
}
},
"endpoint_100_KC_recruitment_change": {
"bounded_multiplicative": {
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"ODOR_B": 0.4
},
"multiplicative": {
"ODOR_A": 0.0,
"ODOR_B": 0.2
}
},
"feedback_causally_isolated_by_this_experiment": false,
"feedback_masks_memory": true,
"gates": {
"bounded_multiplicative": {
"A_KC_spike_L1_mean": 0.0,
"A_MBON_spike_L1_mean": 10.6,
"A_downstream_spike_L1_mean": 741.4,
"A_specific_functional_seeds": 1,
"B_KC_spike_L1_mean": 0.4,
"B_MBON_spike_L1_mean": 12.2,
"B_downstream_spike_L1_mean": 757.0,
"pass": false
},
"multiplicative": {
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"A_MBON_spike_L1_mean": 11.8,
"A_downstream_spike_L1_mean": 901.6,
"A_specific_functional_seeds": 1,
"B_KC_spike_L1_mean": 0.2,
"B_MBON_spike_L1_mean": 15.6,
"B_downstream_spike_L1_mean": 888.0,
"pass": false
}
},
"interpretation": "The prescribed WHOLE-BRAIN-FEEDBACK-MASKS-MEMORY label denotes isolated transfer PASS with whole-brain A/B specificity FAIL. It does not prove feedback is the unique cause; shared plastic edges and baseline network input may also contribute.",
"mean_post_brain_wall_seconds": 1.2878333504500687,
"operational_gate_label_only": true,
"status": "WHOLE-BRAIN-FEEDBACK-MASKS-MEMORY",
"tested_mechanisms": [
"multiplicative",
"bounded_multiplicative"
]
}
}
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