Digital Drosophila Archive
135 lines
4.8 KiB
YAML
135 lines
4.8 KiB
YAML
phase: 4H
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names:
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reference: MaleCNS-LIF-reference-v1
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runtime: MaleCNS-LIF-runtime-v1
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io_api: MaleCNS-BrainIO-v1
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activity_stream: MaleCNS-ActivityStream-v1
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plasticity_candidate: MaleCNS-DopaminePlasticity-v1-candidate
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execution:
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mode: two-stage
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stage1_only_entrypoint: phase4h_audit.py
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require_stage1_pass_before_conditioning: true
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paths:
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connectome_root: /data/digital-drosophila/datasets/male-cns-v1.0/processed/neuron-only
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model_root: /data/digital-drosophila/models/male-cns-lif/dopamine-plasticity-v1
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learned_root: /data/digital-drosophila/models/learned/phase4h
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experiment_root: /data/digital-drosophila/experiments/phase4h-dopamine-plasticity
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reference_root: /data/digital-drosophila/models/male-cns-lif/reference-v1
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runtime_root: /data/digital-drosophila/models/male-cns-lif/runtime-v1
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io_root: /data/digital-drosophila/models/male-cns-lif/io-v1
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phase4c_root: /data/digital-drosophila/experiments/phase4c-runtime
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phase4d_root: /data/digital-drosophila/experiments/phase4d-io
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phase4e_root: /data/digital-drosophila/experiments/phase4e-visual-calibration
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phase4f_root: /data/digital-drosophila/experiments/phase4f-retinotopic-vision
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phase4f_model_root: /data/digital-drosophila/models/male-cns-lif/visual-encoder-v1
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phase4g_root: /data/digital-drosophila/experiments/phase4g-frozen-interface
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phase4g_model_root: /data/digital-drosophila/models/male-cns-lif/frozen-interface-v1
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phase4g_learned_root: /data/digital-drosophila/models/learned/phase4g
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expected_graph:
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neurons: 166700
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directed_edges: 25582938
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synaptic_contact_weight_sum: 124177617
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model:
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dt_ms: 0.1
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membrane_tau_ms: 20.0
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synaptic_tau_ms: 5.0
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refractory_ms: 2.2
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resting_potential_mv: -52.0
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reset_potential_mv: -52.0
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threshold_mv: -45.0
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synaptic_delay_ms: 1.8
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w_syn_mv_per_anatomical_synapse: 0.275
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sign_policy:
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neurotransmitter_sign: {acetylcholine: 1, gaba: -1, glutamate: -1, dopamine: 1, octopamine: 1, serotonin: 1, histamine: -1}
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unknown_sign: 0
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unclear_sign: 0
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readout:
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bins_ms: [1, 5, 10, 20, 50, 100]
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audit:
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exact_class_values:
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KC: Kenyon_Cell
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MBON: MBON
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DAN: DAN
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pam_type_prefix: PAM
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ppl1_type_prefix: PPL1
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compartment_source_field: annotation_instance
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compartment_parser: single_parenthesized_substring_verbatim
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require_exact_compartment_string_match: true
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candidate_requires_actual_kc_mbon_edge: true
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candidate_requires_actual_dan_mbon_edge: true
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candidate_requires_exact_dan_mbon_compartment_match: true
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do_not_infer_missing_compartment_from_type: true
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plasticity:
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base_connectome_mode: read_only
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overlay_equation: effective_weight = base_weight + plastic_delta
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rule: delta_w = polarity_compartment * eta * D_compartment(t) * eligibility_ij(t)
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first_version_rule_family: compartment_specific_dopamine_gated_anti_hebbian_depression
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default_confirmed_compartment_polarity: -1
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unknown_compartment_policy: exclude_from_plastic_mask
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pam_ppl1_cluster_valence_policy: prohibited
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reward_interface_interpretation: artificial_unconditioned_signal_not_dopamine_concentration
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polarity_provenance:
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- https://pubmed.ncbi.nlm.nih.gov/26637800/
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- https://pubmed.ncbi.nlm.nih.gov/25535793/
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- https://www.nature.com/articles/s41586-024-07819-w
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eligibility_tau_ms: 1000.0
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eta_effective_mv: 0.00275
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min_effective_weight_mv: 0.0
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max_fractional_depression_per_edge: 0.25
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training_trials: 3
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d_magnitude: 1.0
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conditioning:
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cs_population: olfactory
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cs_rate_hz: 50.0
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cs_duration_ms: 100.0
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cs_targets_per_identity: 64
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cs_identity_rule: sorted_neuron_idx_disjoint_halves
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appetitive_compartment_verbatim: "y5B'2a"
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appetitive_dan_type_required: PAM15
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aversive_compartment_verbatim: "y2a'1"
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aversive_dan_type_required: PPL103
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delayed_reward_ms: 50.0
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train_seeds: [48001, 48002, 48003, 48004, 48005]
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evaluation_seeds: [48101, 48102, 48103, 48104, 48105]
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protocols:
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- appetitive-conditioning
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- aversive-conditioning
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- reversal-learning
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- delayed-reward
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- retention
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- d-zero-control
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- random-reward-control
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- frozen-brain-control
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reward_interface_label: artificial_unconditioned_signal_interface
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success_gate:
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require_all_frozen_checksums_pass: true
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require_phase4c_reference_spike_events_exact: true
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require_no_nan_inf_or_runaway: true
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require_minimum_seed_majority: 3
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require_appetitive_and_aversive_mbon_separation_gain: true
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require_downstream_separation_gain: true
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require_reversal_signature: true
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require_retention_signature: true
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controls_must_not_equal_conditioning_effect: true
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weight_change_alone_is_never_sufficient: true
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device:
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required_name_substring: RTX 4090
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launcher_visible_gpu_uuid: GPU-79f3a85d-adce-7833-7003-6488140ca596
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prohibitions:
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modify_phase1_to_phase4g: false
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conditioning_during_stage1: false
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weight_update_during_stage1: false
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infer_unknown_mapping: false
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train_base_brain: false
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