Archive MaleCNS research sources, provenance, bibliography and immutable data inventory
This commit is contained in:
Digital Drosophila Archive
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# Phase 4Z — PN feedback and input acceptance audit
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Diagnostic only. No training, no new sign hypothesis, no candidate. The two branches reproduce sealed Phase4Y reference and DPM-off conditions.
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Target and three ALLNs were selected from prior data; this is mechanism exploration, not heldout validation.
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All source fractions are positive arrival-weight accounting, not causal percentages or voltage attribution.
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## Late positive inputs to KC 82312
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| condition | source idx | body_id | type | mean fraction |
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|---|---:|---:|---|---:|
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| DPM_fast_current_off | 30 | 10039 | VL2a_adPN | 0.170584 |
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| DPM_fast_current_off | 179 | 10198 | VA7l_adPN | 0.142137 |
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| DPM_fast_current_off | 368 | 10399 | PPL202 | 0.006085 |
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| DPM_fast_current_off | 484 | 10522 | VL2p_adPN | 0.007661 |
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| DPM_fast_current_off | 1644 | 11761 | VP1d+VP4_l2PN1 | 0.171804 |
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| DPM_fast_current_off | 6065 | 16610 | VA7m_lPN | 0.071431 |
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| DPM_fast_current_off | 6842 | 17484 | DC2_adPN | 0.067442 |
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| DPM_fast_current_off | 133666 | 527577 | VA6_adPN | 0.362856 |
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| frozen_reference | 30 | 10039 | VL2a_adPN | 0.170718 |
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| frozen_reference | 179 | 10198 | VA7l_adPN | 0.141833 |
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| frozen_reference | 368 | 10399 | PPL202 | 0.006249 |
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| frozen_reference | 484 | 10522 | VL2p_adPN | 0.007666 |
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| frozen_reference | 1644 | 11761 | VP1d+VP4_l2PN1 | 0.171787 |
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| frozen_reference | 6065 | 16610 | VA7m_lPN | 0.071424 |
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| frozen_reference | 6842 | 17484 | DC2_adPN | 0.067502 |
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| frozen_reference | 133666 | 527577 | VA6_adPN | 0.362820 |
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## Conditional single-cell replay
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Other recorded arrivals and measured APL remain fixed; original force requests and refractory logic retained. This does not test whole-brain loop necessity.
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| neuron_idx | condition | mode | late spike range |
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|---:|---|---|---:|
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| 30 | DPM_fast_current_off | base | 187–188 |
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| 30 | frozen_reference | base | 187–188 |
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| 179 | DPM_fast_current_off | base | 163–163 |
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| 179 | frozen_reference | base | 162–164 |
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| 484 | DPM_fast_current_off | base | 193–195 |
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| 484 | frozen_reference | base | 193–195 |
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| 1197 | DPM_fast_current_off | base | 228–228 |
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| 1197 | DPM_fast_current_off | omit_ALLN | 217–218 |
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| 1197 | frozen_reference | base | 228–228 |
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| 1197 | frozen_reference | omit_ALLN | 217–218 |
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| 1381 | DPM_fast_current_off | base | 227–228 |
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| 1381 | DPM_fast_current_off | omit_ALLN | 227–228 |
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| 1381 | frozen_reference | base | 227–228 |
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| 1381 | frozen_reference | omit_ALLN | 227–228 |
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| 1511 | DPM_fast_current_off | base | 228–228 |
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| 1511 | DPM_fast_current_off | omit_ALLN | 219–221 |
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| 1511 | frozen_reference | base | 228–228 |
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| 1511 | frozen_reference | omit_ALLN | 219–221 |
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| 1644 | DPM_fast_current_off | base | 217–218 |
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| 1644 | frozen_reference | base | 217–218 |
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| 6065 | DPM_fast_current_off | base | 164–165 |
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| 6065 | frozen_reference | base | 164–165 |
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| 6842 | DPM_fast_current_off | base | 170–171 |
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| 6842 | frozen_reference | base | 170–171 |
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| 82312 | DPM_fast_current_off | base | 60–61 |
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| 82312 | DPM_fast_current_off | omit_ALLN | 60–61 |
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| 82312 | DPM_fast_current_off | omit_ALPN | 0–0 |
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| 82312 | DPM_fast_current_off | omit_DAN | 59–60 |
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| 82312 | DPM_fast_current_off | omit_DPM | 60–61 |
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| 82312 | DPM_fast_current_off | omit_KC | 60–61 |
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| 82312 | DPM_fast_current_off | omit_edge_1646095 | 32–33 |
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| 82312 | DPM_fast_current_off | omit_edge_20992891 | 0–0 |
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| 82312 | DPM_fast_current_off | omit_edge_347756 | 38–39 |
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| 82312 | DPM_fast_current_off | omit_edge_3560137 | 50–50 |
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| 82312 | DPM_fast_current_off | omit_edge_3811419 | 50–51 |
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| 82312 | DPM_fast_current_off | omit_edge_46784 | 33–34 |
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| 82312 | DPM_fast_current_off | omit_edge_749243 | 59–60 |
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| 82312 | frozen_reference | base | 60–61 |
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| 82312 | frozen_reference | omit_ALLN | 60–61 |
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| 82312 | frozen_reference | omit_ALPN | 0–0 |
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| 82312 | frozen_reference | omit_DAN | 59–59 |
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| 82312 | frozen_reference | omit_DPM | 60–61 |
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| 82312 | frozen_reference | omit_KC | 60–61 |
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| 82312 | frozen_reference | omit_edge_1646095 | 32–33 |
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| 82312 | frozen_reference | omit_edge_20992891 | 0–0 |
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| 82312 | frozen_reference | omit_edge_347756 | 37–39 |
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| 82312 | frozen_reference | omit_edge_3560137 | 49–50 |
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| 82312 | frozen_reference | omit_edge_3811419 | 50–51 |
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| 82312 | frozen_reference | omit_edge_46784 | 32–33 |
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| 82312 | frozen_reference | omit_edge_749243 | 58–60 |
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| 133666 | DPM_fast_current_off | base | 212–214 |
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| 133666 | frozen_reference | base | 212–214 |
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## Input acceptance
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| odor | requests | accepted reference | accepted off | status differences | first difference ms |
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|---:|---:|---:|---:|---:|---:|
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| 0 | 131 | 75 | 73 | 8 | 51.8 |
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| 1 | 186 | 77 | 77 | 17 | 57.4 |
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| 2 | 122 | 54 | 52 | 12 | 56.3 |
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| 3 | 95 | 41 | 39 | 3 | 85.3 |
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| 4 | 78 | 31 | 32 | 6 | 54.3 |
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| 5 | 215 | 92 | 91 | 15 | 41.8 |
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Identical requests do not establish matched delivered inputs. Refusal and preexisting spikes depend on endogenous state. No forcing clamp or altered refractory rule was introduced.
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Ancestry edges require actual emission +18 steps <= downstream spike; greedy ranking is not a unique or sufficient causal path. Repeated neuron IDs indicate a time-supported recurrent motif, not proof it is the only sustaining loop.
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Frozen LIF/APL, raw graph/counts, eligibility and masks unchanged. All detailed state/event checks are in regression/.
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@@ -0,0 +1,365 @@
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[
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{
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"categories": [
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"ALLN",
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"ALPN"
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],
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"claim": "ranked time-supported ancestry only; not unique cause or whole-brain necessity",
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"endpoint": "first",
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"hops": 6,
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"neuron_idx": 82312,
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"repeated_neuron_ids": false,
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"root_node": 360,
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"root_step": 14,
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"status": "accepted_input_root",
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"trial": "0-131101-frozen_reference"
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},
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{
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"categories": [
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"ALLN",
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"ALPN"
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],
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"claim": "ranked time-supported ancestry only; not unique cause or whole-brain necessity",
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"endpoint": "first_late",
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"hops": 229,
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"neuron_idx": 82312,
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"repeated_neuron_ids": true,
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"root_node": 360,
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"root_step": 14,
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"status": "accepted_input_root",
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"trial": "0-131101-frozen_reference"
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},
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{
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"categories": [
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"ALLN",
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"ALPN"
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],
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"claim": "ranked time-supported ancestry only; not unique cause or whole-brain necessity",
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"endpoint": "first",
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"hops": 6,
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"neuron_idx": 82312,
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"repeated_neuron_ids": false,
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"root_node": 360,
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"root_step": 14,
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"status": "accepted_input_root",
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"trial": "0-131101-DPM_fast_current_off"
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},
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{
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"categories": [
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"ALLN",
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"ALPN"
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],
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"claim": "ranked time-supported ancestry only; not unique cause or whole-brain necessity",
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"endpoint": "first_late",
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"hops": 226,
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"neuron_idx": 82312,
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"repeated_neuron_ids": true,
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"root_node": 360,
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"root_step": 14,
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"status": "accepted_input_root",
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"trial": "0-131101-DPM_fast_current_off"
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},
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{
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"categories": [
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"ALLN",
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"ALPN"
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],
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"claim": "ranked time-supported ancestry only; not unique cause or whole-brain necessity",
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"endpoint": "first",
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"hops": 4,
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"neuron_idx": 82312,
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"repeated_neuron_ids": false,
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"root_node": 159,
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"root_step": 106,
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"status": "accepted_input_root",
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"trial": "1-131101-frozen_reference"
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},
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{
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"categories": [
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"ALLN",
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"ALPN"
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],
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"claim": "ranked time-supported ancestry only; not unique cause or whole-brain necessity",
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"endpoint": "first_late",
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"hops": 225,
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"neuron_idx": 82312,
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"repeated_neuron_ids": true,
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"root_node": 360,
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"root_step": 70,
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"status": "accepted_input_root",
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"trial": "1-131101-frozen_reference"
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},
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{
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"categories": [
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"ALLN",
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"ALPN"
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],
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"claim": "ranked time-supported ancestry only; not unique cause or whole-brain necessity",
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"endpoint": "first",
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"hops": 4,
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"neuron_idx": 82312,
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"repeated_neuron_ids": false,
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"root_node": 159,
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"root_step": 106,
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"status": "accepted_input_root",
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"trial": "1-131101-DPM_fast_current_off"
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},
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{
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"categories": [
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"ALLN",
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"ALPN"
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],
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"claim": "ranked time-supported ancestry only; not unique cause or whole-brain necessity",
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"endpoint": "first_late",
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"hops": 224,
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"neuron_idx": 82312,
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"repeated_neuron_ids": true,
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"root_node": 360,
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"root_step": 70,
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"status": "accepted_input_root",
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"trial": "1-131101-DPM_fast_current_off"
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},
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{
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"categories": [
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"ALLN",
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"ALPN"
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],
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"claim": "ranked time-supported ancestry only; not unique cause or whole-brain necessity",
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"endpoint": "first",
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"hops": 7,
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"neuron_idx": 82312,
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"repeated_neuron_ids": false,
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"root_node": 522,
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"root_step": 22,
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"status": "accepted_input_root",
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"trial": "2-131101-frozen_reference"
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},
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{
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"categories": [
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"ALLN",
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"ALPN",
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"PN_olfactory_annotation"
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],
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"claim": "ranked time-supported ancestry only; not unique cause or whole-brain necessity",
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"endpoint": "first_late",
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"hops": 210,
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"neuron_idx": 82312,
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"repeated_neuron_ids": true,
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"root_node": 522,
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"root_step": 22,
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"status": "accepted_input_root",
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"trial": "2-131101-frozen_reference"
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},
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{
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"categories": [
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"ALLN",
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"ALPN"
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],
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"claim": "ranked time-supported ancestry only; not unique cause or whole-brain necessity",
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"endpoint": "first",
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"hops": 7,
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"neuron_idx": 82312,
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"repeated_neuron_ids": false,
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"root_node": 522,
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"root_step": 22,
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"status": "accepted_input_root",
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"trial": "2-131101-DPM_fast_current_off"
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},
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{
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"categories": [
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"ALLN",
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"ALPN",
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"PN_olfactory_annotation"
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],
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"claim": "ranked time-supported ancestry only; not unique cause or whole-brain necessity",
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"endpoint": "first_late",
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"hops": 183,
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"neuron_idx": 82312,
|
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"repeated_neuron_ids": true,
|
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"root_node": 522,
|
||||
"root_step": 22,
|
||||
"status": "accepted_input_root",
|
||||
"trial": "2-131101-DPM_fast_current_off"
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},
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{
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"categories": [
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"ALLN",
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"ALPN"
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],
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"claim": "ranked time-supported ancestry only; not unique cause or whole-brain necessity",
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"endpoint": "first",
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"hops": 7,
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"neuron_idx": 82312,
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"repeated_neuron_ids": false,
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"root_node": 189,
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"root_step": 70,
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"status": "accepted_input_root",
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"trial": "3-131101-frozen_reference"
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},
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{
|
||||
"categories": [
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"ALLN",
|
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"ALPN"
|
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],
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"claim": "ranked time-supported ancestry only; not unique cause or whole-brain necessity",
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"endpoint": "first_late",
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"hops": 226,
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"neuron_idx": 82312,
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"repeated_neuron_ids": true,
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"root_node": 2601,
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"root_step": 89,
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"status": "accepted_input_root",
|
||||
"trial": "3-131101-frozen_reference"
|
||||
},
|
||||
{
|
||||
"categories": [
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"ALLN",
|
||||
"ALPN"
|
||||
],
|
||||
"claim": "ranked time-supported ancestry only; not unique cause or whole-brain necessity",
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"endpoint": "first",
|
||||
"hops": 7,
|
||||
"neuron_idx": 82312,
|
||||
"repeated_neuron_ids": false,
|
||||
"root_node": 189,
|
||||
"root_step": 70,
|
||||
"status": "accepted_input_root",
|
||||
"trial": "3-131101-DPM_fast_current_off"
|
||||
},
|
||||
{
|
||||
"categories": [
|
||||
"ALLN",
|
||||
"ALPN"
|
||||
],
|
||||
"claim": "ranked time-supported ancestry only; not unique cause or whole-brain necessity",
|
||||
"endpoint": "first_late",
|
||||
"hops": 225,
|
||||
"neuron_idx": 82312,
|
||||
"repeated_neuron_ids": true,
|
||||
"root_node": 2601,
|
||||
"root_step": 89,
|
||||
"status": "accepted_input_root",
|
||||
"trial": "3-131101-DPM_fast_current_off"
|
||||
},
|
||||
{
|
||||
"categories": [
|
||||
"ALLN",
|
||||
"ALPN"
|
||||
],
|
||||
"claim": "ranked time-supported ancestry only; not unique cause or whole-brain necessity",
|
||||
"endpoint": "first",
|
||||
"hops": 7,
|
||||
"neuron_idx": 82312,
|
||||
"repeated_neuron_ids": false,
|
||||
"root_node": 999,
|
||||
"root_step": 57,
|
||||
"status": "accepted_input_root",
|
||||
"trial": "4-131101-frozen_reference"
|
||||
},
|
||||
{
|
||||
"categories": [
|
||||
"ALLN",
|
||||
"ALPN"
|
||||
],
|
||||
"claim": "ranked time-supported ancestry only; not unique cause or whole-brain necessity",
|
||||
"endpoint": "first_late",
|
||||
"hops": 223,
|
||||
"neuron_idx": 82312,
|
||||
"repeated_neuron_ids": true,
|
||||
"root_node": 999,
|
||||
"root_step": 57,
|
||||
"status": "accepted_input_root",
|
||||
"trial": "4-131101-frozen_reference"
|
||||
},
|
||||
{
|
||||
"categories": [
|
||||
"ALLN",
|
||||
"ALPN"
|
||||
],
|
||||
"claim": "ranked time-supported ancestry only; not unique cause or whole-brain necessity",
|
||||
"endpoint": "first",
|
||||
"hops": 7,
|
||||
"neuron_idx": 82312,
|
||||
"repeated_neuron_ids": false,
|
||||
"root_node": 999,
|
||||
"root_step": 57,
|
||||
"status": "accepted_input_root",
|
||||
"trial": "4-131101-DPM_fast_current_off"
|
||||
},
|
||||
{
|
||||
"categories": [
|
||||
"ALLN",
|
||||
"ALPN"
|
||||
],
|
||||
"claim": "ranked time-supported ancestry only; not unique cause or whole-brain necessity",
|
||||
"endpoint": "first_late",
|
||||
"hops": 226,
|
||||
"neuron_idx": 82312,
|
||||
"repeated_neuron_ids": true,
|
||||
"root_node": 999,
|
||||
"root_step": 57,
|
||||
"status": "accepted_input_root",
|
||||
"trial": "4-131101-DPM_fast_current_off"
|
||||
},
|
||||
{
|
||||
"categories": [
|
||||
"ALLN",
|
||||
"ALPN"
|
||||
],
|
||||
"claim": "ranked time-supported ancestry only; not unique cause or whole-brain necessity",
|
||||
"endpoint": "first",
|
||||
"hops": 6,
|
||||
"neuron_idx": 82312,
|
||||
"repeated_neuron_ids": false,
|
||||
"root_node": 159,
|
||||
"root_step": 42,
|
||||
"status": "accepted_input_root",
|
||||
"trial": "5-131101-frozen_reference"
|
||||
},
|
||||
{
|
||||
"categories": [
|
||||
"ALLN",
|
||||
"ALPN"
|
||||
],
|
||||
"claim": "ranked time-supported ancestry only; not unique cause or whole-brain necessity",
|
||||
"endpoint": "first_late",
|
||||
"hops": 225,
|
||||
"neuron_idx": 82312,
|
||||
"repeated_neuron_ids": true,
|
||||
"root_node": 159,
|
||||
"root_step": 42,
|
||||
"status": "accepted_input_root",
|
||||
"trial": "5-131101-frozen_reference"
|
||||
},
|
||||
{
|
||||
"categories": [
|
||||
"ALLN",
|
||||
"ALPN"
|
||||
],
|
||||
"claim": "ranked time-supported ancestry only; not unique cause or whole-brain necessity",
|
||||
"endpoint": "first",
|
||||
"hops": 6,
|
||||
"neuron_idx": 82312,
|
||||
"repeated_neuron_ids": false,
|
||||
"root_node": 159,
|
||||
"root_step": 42,
|
||||
"status": "accepted_input_root",
|
||||
"trial": "5-131101-DPM_fast_current_off"
|
||||
},
|
||||
{
|
||||
"categories": [
|
||||
"ALLN",
|
||||
"ALPN",
|
||||
"PN_olfactory_annotation"
|
||||
],
|
||||
"claim": "ranked time-supported ancestry only; not unique cause or whole-brain necessity",
|
||||
"endpoint": "first_late",
|
||||
"hops": 192,
|
||||
"neuron_idx": 82312,
|
||||
"repeated_neuron_ids": true,
|
||||
"root_node": 159,
|
||||
"root_step": 42,
|
||||
"status": "accepted_input_root",
|
||||
"trial": "5-131101-DPM_fast_current_off"
|
||||
}
|
||||
]
|
||||
+15
@@ -0,0 +1,15 @@
|
||||
{
|
||||
"scope": "static coverage of frozen DeterministicAPLSim.install and graded output matrix; not proof of functional effect",
|
||||
"APL_neurons": 2,
|
||||
"all_outgoing_edges": 5845,
|
||||
"all_outgoing_synapse_count": 209912,
|
||||
"non_KC_edges_without_graded_replacement": 1212,
|
||||
"non_KC_synapse_count_without_graded_replacement": 13712,
|
||||
"non_KC_target_neurons": 999,
|
||||
"watched_PN_edges": 7,
|
||||
"watched_PN_synapse_count": 247,
|
||||
"source": "/data/digital-drosophila/models/male-cns-lif/deterministic-runtime-v2/phase4p_revalidate.py",
|
||||
"source_sha256": "c7e693a2da70acdce4f53af5c2853e52e8333acc93f88a46a5e8083eac639346",
|
||||
"baseline_not_modified": true,
|
||||
"cannot_replace_terminal_inhibition_with_whole_PN_inhibition_without_new_hypothesis": true
|
||||
}
|
||||
@@ -0,0 +1,87 @@
|
||||
# Phase 4Z — mechanism interpretation
|
||||
|
||||
Post-run descriptive analysis, not a new candidate gate. No tuning, learning, new stimulus or sign hypothesis.
|
||||
The earlier generic label PN feedback is refined below using actual ALLN cell identities. Do not assume the residual loop is KC→MBON→PN feedback merely because that pathway exists in the literature.
|
||||
|
||||
## Watched identities
|
||||
|
||||
| neuron_idx | body_id | class | type | metadata transmitter | raw ground_truth |
|
||||
|---:|---:|---|---|---|---|
|
||||
| 30 | 10039 | ALPN | VL2a_adPN | acetylcholine | acetylcholine |
|
||||
| 179 | 10198 | ALPN | VA7l_adPN | acetylcholine | acetylcholine |
|
||||
| 484 | 10522 | ALPN | VL2p_adPN | acetylcholine | acetylcholine |
|
||||
| 1197 | 11289 | ALLN | lLN1_bc | acetylcholine | acetylcholine |
|
||||
| 1381 | 11478 | ALLN | lLN1_bc | acetylcholine | acetylcholine |
|
||||
| 1511 | 11620 | ALLN | lLN1_bc | acetylcholine | acetylcholine |
|
||||
| 1644 | 11761 | ALPN | VP1d+VP4_l2PN1 | acetylcholine | None |
|
||||
| 6065 | 16610 | ALPN | VA7m_lPN | acetylcholine | acetylcholine |
|
||||
| 6842 | 17484 | ALPN | DC2_adPN | acetylcholine | acetylcholine |
|
||||
| 82312 | 109321 | Kenyon_Cell | KC | acetylcholine | None |
|
||||
| 133666 | 527577 | ALPN | VA6_adPN | acetylcholine | acetylcholine |
|
||||
|
||||
## Representative first-late ancestry
|
||||
|
||||
Odor 0 / seed 131101 / frozen reference. Ordered source spike → edge arrival → target spike (ms). These are ranked event-supported contributions; no unique predecessor assertion.
|
||||
| source idx/type | target idx/type | source time | arrival time | target time | contacts | effective weight |
|
||||
|---|---|---:|---:|---:|---:|---:|
|
||||
| 1381/lLN1_bc | 1511/lLN1_bc | 496.1 | 497.9 | 498.3 | 235 | 64.625000 |
|
||||
| 1511/lLN1_bc | 1381/lLN1_bc | 498.3 | 500.1 | 500.5 | 283 | 77.825005 |
|
||||
| 1381/lLN1_bc | 1197/lLN1_bc | 500.5 | 502.3 | 502.6 | 259 | 71.224998 |
|
||||
| 1197/lLN1_bc | 133666/VA6_adPN | 502.6 | 504.4 | 504.5 | 104 | 28.600000 |
|
||||
| 133666/VA6_adPN | 82312/KC | 504.5 | 506.3 | 506.4 | 43 | 11.825000 |
|
||||
|
||||
## Dominant PN arrival contribution
|
||||
|
||||
| trial | PN idx/type | positive arrival fraction |
|
||||
|---|---|---:|
|
||||
| 0-131101-DPM_fast_current_off | 133666/VA6_adPN | 36.213% |
|
||||
| 0-131101-frozen_reference | 133666/VA6_adPN | 36.346% |
|
||||
| 1-131101-DPM_fast_current_off | 133666/VA6_adPN | 36.353% |
|
||||
| 1-131101-frozen_reference | 133666/VA6_adPN | 36.346% |
|
||||
| 2-131101-DPM_fast_current_off | 133666/VA6_adPN | 36.339% |
|
||||
| 2-131101-frozen_reference | 133666/VA6_adPN | 36.223% |
|
||||
| 3-131101-DPM_fast_current_off | 133666/VA6_adPN | 36.243% |
|
||||
| 3-131101-frozen_reference | 133666/VA6_adPN | 36.162% |
|
||||
| 4-131101-DPM_fast_current_off | 133666/VA6_adPN | 36.183% |
|
||||
| 4-131101-frozen_reference | 133666/VA6_adPN | 36.223% |
|
||||
| 5-131101-DPM_fast_current_off | 133666/VA6_adPN | 36.383% |
|
||||
| 5-131101-frozen_reference | 133666/VA6_adPN | 36.393% |
|
||||
|
||||
Fractions are sums of positive synaptic arrivals, not percentages of causal responsibility. Negative input, recorded APL and membrane dynamics are retained in exact CPU replay.
|
||||
The preidentified 1381↔1511 event motif occurs in 7/12 first-late ancestry paths. Full temporal edges and alternative inputs are retained.
|
||||
Conditional omission results are in replay/results.parquet and REPORT.md. They retain other source events; loss of spikes there is not evidence that a whole-brain ablation would produce the same result.
|
||||
Critically, omitting ALLN arrivals to a watched ALLN does not silence it in conditional replay: recorded PN and other inputs can still sustain high firing. Thus the 1381↔1511 motif cannot be called the sole cause or an isolated autonomous oscillator.
|
||||
Removing the existing VA6_adPN→KC82312 edge in conditional replay eliminates target late firing; removing ALLN input to VA6_adPN also eliminates its late firing. These are two conditional links, not a demonstrated whole-brain necessity chain.
|
||||
|
||||
## Late firing of preidentified ALLNs
|
||||
|
||||
| neuron_idx | late rate range Hz | min/max ISI ms | fraction ISI = refractory, range |
|
||||
|---:|---:|---:|---:|
|
||||
| 1197 | 456–456 | 2.20/2.20 | 1.00000–1.00000 |
|
||||
| 1381 | 454–456 | 2.20/2.20 | 1.00000–1.00000 |
|
||||
| 1511 | 456–456 | 2.20/2.20 | 1.00000–1.00000 |
|
||||
|
||||
This is a measured property of the mathematical model, not a validated biological firing rate. Window-boundary counting can put spikes/window slightly above 1/refractory. No new biological runaway threshold is inferred.
|
||||
|
||||
## Frozen APL replacement target coverage
|
||||
|
||||
The frozen implementation zeroes all 5845 APL fast outgoing edges and reintroduces graded inhibition only on KC targets. 1212 non-KC edges (13712 anatomical contacts) have no direct graded replacement in this implementation.
|
||||
This includes 7 edges / 247 anatomical contacts onto the seven watched PNs. Raw edges and counts remain intact. These edges were not removed by this audit.
|
||||
This is an implementation coverage gap relative to the anatomical graph, not evidence that restoring a whole-neuron negative current would be biologically correct. APL inhibition of PN boutons is spatial/terminal-specific and a point-neuron approximation may not capture it.
|
||||
Primary study: Prisco et al., eLife 10:e74172 (2021), https://pubmed.ncbi.nlm.nih.gov/34964714/ . It reports reciprocal APL inhibition targeting PN boutons and KC dendrites; it does not provide these MaleCNS edge-specific effective parameters.
|
||||
No frozen APL parameter, edge, sign or output target was modified. Functional necessity of this coverage gap remains untested.
|
||||
|
||||
## What input matching means
|
||||
|
||||
All six paired request schedules match. Status differs for 61 requests in total; actual output at requested times differs for 52 requests.
|
||||
An accepted→preexisting transition changes the accepted-new count without removing the output spike. A blocked transition can change actual delivery. Thus accepted-new totals alone are insufficient to describe input matching.
|
||||
The first differing request is state dependent; this is an endogenous response to an existing intervention, not evidence of different external RNG. No clamp, injected substitute events or refractory override was introduced.
|
||||
The earlier closed-loop intervention remains interpretable as a total system effect under matched requests. It is not an estimate of a direct DPM effect holding actual PN output trains fixed.
|
||||
|
||||
## Literature boundary
|
||||
|
||||
Excitatory local antennal-lobe circuits and reciprocal local-neuron/PN excitation have experimental support. They must not automatically be relabeled inhibitory because the model has persistent activity.
|
||||
Shang et al., Cell 2007: https://pubmed.ncbi.nlm.nih.gov/17289577/
|
||||
Huang et al., Neuron 2010, functional connectivity of excitatory local interneurons: https://doi.org/10.1016/j.neuron.2010.08.025
|
||||
These experiments do not validate uniform current weights, this MaleCNS individual, or its simulated persistent firing. No receptor, adaptation or electrical-synapse parameters are inferred or inserted.
|
||||
Next priority is independent assessment of local AL-loop dynamics and input-interface causal controls, not changing dopamine learning rate. No official model replacement is justified.
|
||||
+7
@@ -0,0 +1,7 @@
|
||||
{
|
||||
"source": "/data/digital-drosophila/models/male-cns-lif/pn-feedback-audit-v1/phase4z_describe.py",
|
||||
"sha256": "d2007b312b587cc105f13b3ef68c64fb145e7b30a6addfe789a0558c365a0b36",
|
||||
"post_run_descriptive_analysis": true,
|
||||
"not_part_of_simulation_preregistration": true,
|
||||
"new_simulations_or_selection": false
|
||||
}
|
||||
+231
@@ -0,0 +1,231 @@
|
||||
{
|
||||
"history": {
|
||||
"Phase1_to_3B": {
|
||||
"all_passed": true,
|
||||
"phase1_phase2_backup_sha256": {
|
||||
"passed": true,
|
||||
"returncode": 0,
|
||||
"stderr": ""
|
||||
},
|
||||
"phase3_sha256": {
|
||||
"passed": true,
|
||||
"returncode": 0,
|
||||
"stderr": ""
|
||||
},
|
||||
"phase3b_166700_sha256": {
|
||||
"passed": true,
|
||||
"returncode": 0,
|
||||
"stderr": ""
|
||||
},
|
||||
"phase3b_audit_sha256": {
|
||||
"passed": true,
|
||||
"returncode": 0,
|
||||
"stderr": ""
|
||||
},
|
||||
"raw_core_sha256": {
|
||||
"passed": true,
|
||||
"returncode": 0,
|
||||
"stderr": ""
|
||||
},
|
||||
"raw_skeleton_md5": {
|
||||
"passed": true,
|
||||
"returncode": 0,
|
||||
"stderr": ""
|
||||
}
|
||||
},
|
||||
"Phase4C_to_4L": {
|
||||
"all_passed": true,
|
||||
"phase4c_to_4i": true,
|
||||
"phase4j_to_4l": {
|
||||
"phase4j_model_root": true,
|
||||
"phase4j_root": true,
|
||||
"phase4k_model_root": true,
|
||||
"phase4k_root": true,
|
||||
"phase4l_model_root": true,
|
||||
"phase4l_root": true
|
||||
}
|
||||
},
|
||||
"Phase4M_4N": {
|
||||
"Phase4M experiment": {
|
||||
"checked": 80,
|
||||
"control": "/data/digital-drosophila/experiments/phase4m-kcmbon-efficacy/manifests/checksums.sha256",
|
||||
"failures": [],
|
||||
"passed": true,
|
||||
"root": "/data/digital-drosophila/experiments/phase4m-kcmbon-efficacy"
|
||||
},
|
||||
"Phase4M model": {
|
||||
"checked": 7,
|
||||
"control": "/data/digital-drosophila/models/male-cns-lif/kcmbon-efficacy-v1/checksums.sha256",
|
||||
"failures": [],
|
||||
"passed": true,
|
||||
"root": "/data/digital-drosophila/models/male-cns-lif/kcmbon-efficacy-v1"
|
||||
},
|
||||
"Phase4N experiment": {
|
||||
"checked": 396,
|
||||
"control": "/data/digital-drosophila/experiments/phase4n-credit-assignment/manifests/checksums.sha256",
|
||||
"failures": [],
|
||||
"passed": true,
|
||||
"root": "/data/digital-drosophila/experiments/phase4n-credit-assignment"
|
||||
},
|
||||
"Phase4N model": {
|
||||
"checked": 12,
|
||||
"control": "/data/digital-drosophila/models/male-cns-lif/credit-assignment-v1/checksums.sha256",
|
||||
"failures": [],
|
||||
"passed": true,
|
||||
"root": "/data/digital-drosophila/models/male-cns-lif/credit-assignment-v1"
|
||||
}
|
||||
},
|
||||
"Phase4O": {
|
||||
"checked": 40,
|
||||
"control": "/data/digital-drosophila/experiments/phase4o-runtime-credit/manifests/checksums.sha256",
|
||||
"failures": [],
|
||||
"passed": true,
|
||||
"root": "/data/digital-drosophila/experiments/phase4o-runtime-credit"
|
||||
},
|
||||
"all_static_checks_passed": true,
|
||||
"frozen_input_hashes_unchanged": true
|
||||
},
|
||||
"inputs": {
|
||||
"P": {
|
||||
"checked": 86,
|
||||
"control": "/data/digital-drosophila/experiments/phase4p-deterministic-runtime/manifests/checksums.sha256",
|
||||
"failures": [],
|
||||
"passed": true,
|
||||
"root": "/data/digital-drosophila/experiments/phase4p-deterministic-runtime"
|
||||
},
|
||||
"P_candidate": {
|
||||
"checked": 10,
|
||||
"control": "/data/digital-drosophila/models/male-cns-lif/deterministic-runtime-v2/candidate/checksums.sha256",
|
||||
"failures": [],
|
||||
"passed": true,
|
||||
"root": "/data/digital-drosophila/models/male-cns-lif/deterministic-runtime-v2/candidate"
|
||||
},
|
||||
"Q": {
|
||||
"checked": 24,
|
||||
"control": "/data/digital-drosophila/experiments/phase4q-credit-v3/manifests/checksums.sha256",
|
||||
"failures": [],
|
||||
"passed": true,
|
||||
"root": "/data/digital-drosophila/experiments/phase4q-credit-v3"
|
||||
},
|
||||
"Q_model": {
|
||||
"checked": 6,
|
||||
"control": "/data/digital-drosophila/models/male-cns-lif/credit-v3/checksums.sha256",
|
||||
"failures": [],
|
||||
"passed": true,
|
||||
"root": "/data/digital-drosophila/models/male-cns-lif/credit-v3"
|
||||
},
|
||||
"R": {
|
||||
"checked": 205,
|
||||
"control": "/data/digital-drosophila/experiments/phase4r-timing-audit/checksums.sha256",
|
||||
"failures": [],
|
||||
"passed": true,
|
||||
"root": "/data/digital-drosophila/experiments/phase4r-timing-audit"
|
||||
},
|
||||
"R_model": {
|
||||
"checked": 5,
|
||||
"control": "/data/digital-drosophila/models/male-cns-lif/timing-audit-v1/checksums.sha256",
|
||||
"failures": [],
|
||||
"passed": true,
|
||||
"root": "/data/digital-drosophila/models/male-cns-lif/timing-audit-v1"
|
||||
},
|
||||
"U_prior_model": {
|
||||
"checked": 5,
|
||||
"control": "/data/digital-drosophila/models/male-cns-lif/odor-timing-generalization-v1/checksums.sha256",
|
||||
"failures": [],
|
||||
"passed": true,
|
||||
"root": "/data/digital-drosophila/models/male-cns-lif/odor-timing-generalization-v1"
|
||||
},
|
||||
"U_prior_root": {
|
||||
"checked": 150,
|
||||
"control": "/data/digital-drosophila/experiments/phase4u-odor-generalization/checksums.sha256",
|
||||
"failures": [],
|
||||
"passed": true,
|
||||
"root": "/data/digital-drosophila/experiments/phase4u-odor-generalization"
|
||||
},
|
||||
"V_prior_model": {
|
||||
"checked": 5,
|
||||
"control": "/data/digital-drosophila/models/male-cns-lif/csus-audit-v1/checksums.sha256",
|
||||
"failures": [],
|
||||
"passed": true,
|
||||
"root": "/data/digital-drosophila/models/male-cns-lif/csus-audit-v1"
|
||||
},
|
||||
"V_prior_root": {
|
||||
"checked": 244,
|
||||
"control": "/data/digital-drosophila/experiments/phase4v-csus-semantics/checksums.sha256",
|
||||
"failures": [],
|
||||
"passed": true,
|
||||
"root": "/data/digital-drosophila/experiments/phase4v-csus-semantics"
|
||||
},
|
||||
"X_prior_model": {
|
||||
"checked": 5,
|
||||
"control": "/data/digital-drosophila/models/male-cns-lif/transmitter-audit-v1/checksums.sha256",
|
||||
"failures": [],
|
||||
"passed": true,
|
||||
"root": "/data/digital-drosophila/models/male-cns-lif/transmitter-audit-v1"
|
||||
},
|
||||
"X_prior_root": {
|
||||
"checked": 124,
|
||||
"control": "/data/digital-drosophila/experiments/phase4x-transmitter-provenance/checksums.sha256",
|
||||
"failures": [],
|
||||
"passed": true,
|
||||
"root": "/data/digital-drosophila/experiments/phase4x-transmitter-provenance"
|
||||
},
|
||||
"Z_input_event_experiment": {
|
||||
"checked": 214,
|
||||
"control": "/data/digital-drosophila/experiments/phase4w-late-kc-feedback/checksums.sha256",
|
||||
"failures": [],
|
||||
"passed": true,
|
||||
"root": "/data/digital-drosophila/experiments/phase4w-late-kc-feedback"
|
||||
},
|
||||
"Z_input_prior_model": {
|
||||
"checked": 5,
|
||||
"control": "/data/digital-drosophila/models/male-cns-lif/dpm-hypothesis-v1/checksums.sha256",
|
||||
"failures": [],
|
||||
"passed": true,
|
||||
"root": "/data/digital-drosophila/models/male-cns-lif/dpm-hypothesis-v1"
|
||||
},
|
||||
"Z_input_prior_root": {
|
||||
"checked": 145,
|
||||
"control": "/data/digital-drosophila/experiments/phase4y-dpm-hypothesis/checksums.sha256",
|
||||
"failures": [],
|
||||
"passed": true,
|
||||
"root": "/data/digital-drosophila/experiments/phase4y-dpm-hypothesis"
|
||||
},
|
||||
"prior_addendum": {
|
||||
"checked": 5,
|
||||
"control": "/data/digital-drosophila/experiments/phase4w-transmitter-interpretation/checksums.sha256",
|
||||
"failures": [],
|
||||
"passed": true,
|
||||
"root": "/data/digital-drosophila/experiments/phase4w-transmitter-interpretation"
|
||||
},
|
||||
"prior_model": {
|
||||
"checked": 4,
|
||||
"control": "/data/digital-drosophila/models/male-cns-lif/late-kc-audit-v1/checksums.sha256",
|
||||
"failures": [],
|
||||
"passed": true,
|
||||
"root": "/data/digital-drosophila/models/male-cns-lif/late-kc-audit-v1"
|
||||
},
|
||||
"prior_root": {
|
||||
"checked": 214,
|
||||
"control": "/data/digital-drosophila/experiments/phase4w-late-kc-feedback/checksums.sha256",
|
||||
"failures": [],
|
||||
"passed": true,
|
||||
"root": "/data/digital-drosophila/experiments/phase4w-late-kc-feedback"
|
||||
},
|
||||
"source_model": {
|
||||
"checked": 4,
|
||||
"control": "/data/digital-drosophila/models/male-cns-lif/timing-credit-v1/checksums.sha256",
|
||||
"failures": [],
|
||||
"passed": true,
|
||||
"root": "/data/digital-drosophila/models/male-cns-lif/timing-credit-v1"
|
||||
},
|
||||
"source_root": {
|
||||
"checked": 46,
|
||||
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File diff suppressed because it is too large
Load Diff
Reference in New Issue
Block a user