phase: 4I
name: MaleCNS-MB-mechanistic-validation-v1

paths:
  connectome_root: /data/digital-drosophila/datasets/male-cns-v1.0/processed/neuron-only
  model_root: /data/digital-drosophila/models/male-cns-lif
  phase4i_model_root: /data/digital-drosophila/models/male-cns-lif/mb-mechanistic-v1
  experiment_root: /data/digital-drosophila/experiments/phase4i-mb-mechanistic-validation
  reference_root: /data/digital-drosophila/models/male-cns-lif/reference-v1
  runtime_root: /data/digital-drosophila/models/male-cns-lif/runtime-v1
  io_root: /data/digital-drosophila/models/male-cns-lif/io-v1
  phase4c_root: /data/digital-drosophila/experiments/phase4c-runtime
  phase4d_root: /data/digital-drosophila/experiments/phase4d-io
  phase4e_root: /data/digital-drosophila/experiments/phase4e-visual-calibration
  phase4f_root: /data/digital-drosophila/experiments/phase4f-retinotopic-vision
  phase4f_model_root: /data/digital-drosophila/models/male-cns-lif/visual-encoder-v1
  phase4g_root: /data/digital-drosophila/experiments/phase4g-frozen-interface
  phase4g_model_root: /data/digital-drosophila/models/male-cns-lif/frozen-interface-v1
  phase4g_learned_root: /data/digital-drosophila/models/learned/phase4g
  phase4h_root: /data/digital-drosophila/experiments/phase4h-dopamine-plasticity
  phase4h_model_root: /data/digital-drosophila/models/male-cns-lif/dopamine-plasticity-v1
  phase4h_learned_root: /data/digital-drosophila/models/learned/phase4h

expected_graph:
  neurons: 166700
  directed_edges: 25582938
  synaptic_contact_weight_sum: 124177617
  phase4h_plastic_candidate_edges: 14232

names:
  reference: MaleCNS-LIF-reference-v1
  runtime: MaleCNS-LIF-runtime-v1

model:
  dt_ms: 0.1
  membrane_tau_ms: 20.0
  synaptic_tau_ms: 5.0
  refractory_ms: 2.2
  resting_potential_mv: -52.0
  reset_potential_mv: -52.0
  threshold_mv: -45.0
  synaptic_delay_ms: 1.8
  w_syn_mv_per_anatomical_synapse: 0.275

sign_policy:
  neurotransmitter_sign: {acetylcholine: 1, gaba: -1, glutamate: -1, dopamine: 1, octopamine: 1, serotonin: 1, histamine: -1}
  unknown_sign: 0
  unclear_sign: 0

readout:
  bins_ms: [1, 5, 10, 20, 50, 100]

device:
  required_name_substring: RTX 4090
  launcher_visible_gpu_uuid: GPU-79f3a85d-adce-7833-7003-6488140ca596

olfactory_audit:
  seeds: [48101, 48102, 48103, 48104, 48105]
  rate_hz: 50.0
  duration_ms: 100.0
  targets_per_identity: 64
  temporal_bin_ms: 10.0
  consensus_seed_count: 3
  separability_gate:
    maximum_mean_active_jaccard: 0.8
    minimum_pair_cosine_distance: 0.01
    majority_seeds: 3
    between_exceeds_within_sigma: 2.0

direct_kc:
  ensemble_size: 64
  target_compartment_verbatim: "y5B'2a"
  matched_dan_type: PAM15
  unrelated_compartment_verbatim: "y2a'1"
  unrelated_dan_type: PPL103
  pulse_times_ms: [10.0, 30.0, 50.0, 70.0, 90.0]
  evaluation_duration_ms: 120.0
  conditioning_trials: 3
  train_seeds: [49001, 49002, 49003, 49004, 49005]
  evaluation_seeds: [49101, 49102, 49103, 49104, 49105]

plasticity:
  overlay_equation: effective_weight = base_weight + plastic_delta
  eta_effective_mv: 0.00275
  eligibility_tau_ms: 1000.0
  polarity: -1
  max_fractional_depression_per_edge: 0.25
  negative_delay_behavior_under_phase4h_rule: full_eligibility

timing:
  delta_t_ms: [-1000, -500, -250, -100, -50, 0, 50, 100, 250, 500, 1000]
  common_kc_time_ms: 1000.0
  trial_duration_ms: 2100.0
  seed: 49201
  far_to_coincident_nonspecific_ratio: 0.1

controls:
  conditions: [A-matched-DAN, A-D-zero, A-unrelated-DAN, B-matched-DAN, random-KC-DAN, frozen-no-plasticity]

prohibitions:
  modify_base_csr: false
  modify_w_syn: false
  modify_transmitter_sign: false
  modify_lif_parameters: false
  expand_plastic_mask: false
  tune_eta_or_polarity: false
  brain_backpropagation: false
  reinforcement_learning: false
  visual_or_game_integration: false